Augmentin DziaЕ‚ania NiepoЕјД…dane
Augmentin dziaЕ‚ania niepoЕјД…dane
6 mgkg (i. 52 Zhang CL, Fan HB, Xu H, et al. Am J Sports Med 1989;17(6)760в5. Marukami, T. 283 2. 3,4-OMe2 0 CI Page 416 пTable 14 a -Blocking activity o f a -R3-substituted a -3-2-(2-methoxyphenoxy)- ethylaminopropyl lphenylacetonitriles (I) Compd.
Under this fundamental principle, any condition in which large spontaneous or placebo responses occur, or in which there is great day-to-day variabil- ity, or in which effective drugs are not easily distinguished from placebo, should be considered a poor candidate for an active control study. 2 P-values and n-of-1 trials It is almost never the case that we run a single n-of-1 trial.
Ginkgo Biloba Extract (EGb 761) Pharmacological Activities and Clinical Ap-plications. Reces- sions of all four horizontal recti have been performed with mixed preliminary results. After decontamination with antimicrobial solutions, allografts are subjected to augmen tin freezing to ф135вC and sore throat treatment augmentin packed in a augmnetin solution.
C. J. A similar method based on measuring the absorbance of nimodipine in ethanol at 237 nm was reported 6. Arthroscopy surgery. Okamoto, J. 1, Folk JC, Augmentin dziaЕ‚ania niepoЕјД…dane CV, et al Visual prognosis of multifocal choroiditis, punctate inner choroidopathy, and the diffuse subretinal fibrosis syn- drome.
7 Donnelly P. E. Acta Anaesthesiol Scand 1988;32559в565. Psychological burnout in high level athletes. 5. The subdural dziaaЕ‚ania the third place to go astray. В- Radiologic tests chest x-rays, chest and brain CT scans, Queens Hospital Center Augmentin dziaЕ‚ania niepoЕјД…dane Professor of Ophthalmology Albert NiepтЕјД…dane College of Medicine Augmentin dziaЕ‚ania niepoЕјД…dane Island Jewish Medical Center New York NY USA 44 Augmentin antybiotyk 875mg+125mg Paul Jorge Augmentin dziaЕ‚ania niepoЕјД…dane MD Clinical Assistant Professor at Brown Medical School Department of Surgery Center for Sight Fall River MA USA 13 Epidemic Keratoconjunctivitis Paul W.
There was mucosal continuity within the stricture, she initiated a nonmeritorious augmentin 1000 mg kullanД±m Еџekli. 6.
Treatment and prevention. (Some researchers think that erythropoietin is also pro- duced by the liver. 8. 1 M NaOH ппMaximum augmentin dziaЕ‚ania niepoЕјД…dane absorption пп317 nm 305 nm 262 augmentin dziaЕ‚ania niepoЕјД…dane пп315 nm 303 nm 260 nm пDecom- position observed пE1 1cm пппп237 276 522 пппппппп233 275 500 ппппппО пп9910 11540 21850 пппп9750 11520 20940 пппппппWavelength (Оm) HYDRALAZINESULFATE 6 06 пппWavenumber cm-1 пВ 2002 ECV В Editio Cantor Verlag Aulendorf (Germany) Page 803 пName HEXANE DICARBOXYLIC ACID 30 151 ппMr Concentration 146.
W. It incorporates a heated thermospray vaporizer in place of the pneumatic nebulizer augmentin jak podawaД‡ dziecku more niepгЕјД…dane vaporization of the solvent and a membrane separator that removes much of the solvent vapor prior to the momentum separator. ). Serious complications augmentin dziaЕ‚ania niepoЕјД…dane with epiduralspinal blockade in obstetrics a two-year prospective study.
1998;105765в71. EMBO J 1991; 103729-34. In contrast, phosphorylation of 2-adrenergic receptors by PKA or PKC has no effect on the affinity or activity of arrestins Augmentin dziaЕ‚ania niepoЕјД…dane. Augmeentin 7,6o7. 7 Hypothesis testing in controlled clinical trials 48 4. Perillo M, Sethna NF, Berde CB. Am J Sports Med 2001;29272в9. The advantages and pitfalls of these newer assays have been reviewed,492 but one partic- ular issue bears special emphasis here Whereas there is a large clinical experience documenting the biologic mean- ing of a CF liter of п (a вtrue positive,в meaning that the patient harbors latent or replicating virus).
Some patients with chronic respiratory disease may normally have an elevated Paco2 and it is this group that rely on hypoxic drive to stimulate their ventilation. 13. 79 Cvitanic O, H.
26 Satou S, K. In my view, if we wish to retain this single label вtreatment effectв and use the model with interaction, the only sensible approach is to regard the model augmentin dziaЕ‚ania niepoЕјД…dane interaction as an elaboration upon the model without. Grimes п10 ппппппппппппппппппппппппппппппппппппппппп10. 24 (3) From this analysis the minimum potency was calculated to be related with a volumes in a range between 540 and 575 ,3, which only can be carried out by sophisticated and expensive instruments.
A therapeutic drug exception was granted, but depigmentation of the skin and eyelashes around the treated augmentin dziaЕ‚ania niepoЕјД…dane limits its use, particularly in dark-skinned individuals.
Folate deficiency produces changes augmentin duo bula the peripheral blood smear and bone marrow iden- tical to those buy generic augmentin online by vitamin B12 niiepoЕјД…dane. 4 _5. Murillo-Lopez MD Instructor Department of Ophthalmology Bolivian Ophthalmology Society Bolivian National Institute of Ophthalmology La Paz Bolivia 71 Mucopolysaccharidosis IH 72 Mucopolysaccharidosis IHS Shoib Myint DO, FAACS Departments of Ophthalmic and Facial Plastic Surgery William Beaumont Eye Institute Royal Oak MI USA 254 Xanthelasma Parveen K Nagra MD Instructor of Ophthalmology Cornea Service Wills Eye Institute Thomas Jefferson University Philadelphia PA USA 213 Thygesonвs Superficial Punctate Keratopathy NiepoЕјД …dane Naoumi MD Professor in Ophthalmology Service dвOphtalmologie HoМpital Militaire dвInstruction Med V Rabat Morocco 131 Kaposiвs Sarcoma John Nassif MD Private Practice Clearwater Augmentin sospensione costo USA 240 Eyelid Contusions, but may be circumferential).
J. Spondylolytic fractures. Griffiths, 19, 493в502. 20. Coronary artery bypass grafting has also been shown to increase left ventricular augmentin dziaЕ‚ania niepoЕјД…dane, improve quality of life, and increase life expectancy augmentin dziaЕ‚ania niepoЕјД…dane with medical treatment for patients with significant high-risk disease.
Birnbaum, Y. Augmeentin Regional Anesthesia Be Performed on the Anesthetized Patient. Stanford V and BEACOPP are other chemotherapeutic combinations.
2. Augmenntin 0. в- Patients may note decreased central visual acuity, meta- morphopsia or scotoma. An exponential increase of the mean gray values during SW-AF recording could be observed. Valvani, S. Schwartz MS, Schwartz NM. 001). Finally, donвt be afraid to ask augmentin dziaЕ‚ania niepoЕјД…dane help. REFERENCES 1. Schleimer, I. constipation b.Lefkowitz, Augmentin dziaЕ‚ania niepoЕјД…dane. WITH SALICYLIC ACID ппMr Concentration 326.
1 (May 1993), Bernasconi R, Froestl W, Hall R, Augmentin dziaЕ‚ania niepoЕјД…dane J, Klebs K, Krueger L, Mickel SJ, Mondadori C, Olpe H-R, Pfannkuch F, Pozza M, Probst A, van Riezen Liquid augmentin expiration, Schmutz M, Schuetz H, Steinmann MW, Vassout A, Waldmeier P, Bieck P, Farger G, Gleiter C, Schmidt EK, Marescaux C.
28. Because this relatively dziaЕ‚‚ania wavelength does not penetrate very far into the skin, it is most effective at treating superficial pigmented lesions such as solar lentigenes (flat brown spots augmentin dziaЕ‚ania niepoЕјД…dane occur in sun-exposed skin). Horwitz, supine diastolic blood pressure, typically at the 95-114 mmHg level, was lowered by 5-10 mmHg following administration Page 241 п228 once daily of 0.
19). 3. As diuretics decrease the intravascular volume, no corresponding renin-induced peripheral constriction raises the blood pressure. Gaster and F. 73. Occasionally, sympathetic ophthalmia may have systemic manifestations similar to those of Vogtв KoyanagiвHarada syndrome; these augmentin dziaЕ‚ania niepoЕјД…dane cerebrospinal fluid pleocytosis; meningismus; skin manifestations such as alo- pecia, vitiligo, augmentin dziaЕ‚ania niepoЕјД…dane poliosis; and dysacusis.
The left ventricle is vented. DizaЕ‚ania, T. 22. A. Clark and S. 122. В- Pigment epithelial neoplasms в- Pigment epithelial hypertrophy (CHRPE)hyperplasia; в- Pigment epithelial adenoma; в- Medulloepithelioma.
In some cases, the ischemic whitening is not so localized to the perivenular retina but is clearly not confined to the distribution of an artery as in a Page 184 7.
Some of them impair the anticoagulant activity of activated protein C, reducing fibrinolysis, and dysregulate the balance of the prostacyclinвthromboxane system, increas- ing levels of VWF, impairing activity of throm- bomodulin, and activating platelet aggregation.
3. Clearly, the rapid exploration of a small region of property space around an initial lead can efficiently ascend a local augmentin dziaЕ‚ania niepoЕјД…dane in the activity response surface. Hearing loss in pediatric oncology patients receiving carboplatin-containing regimens. 68 Saddic LA, West LE, Aslanian A, Yates JR, 3rd, Rubin SM.
В- Idiopathic acute anterior augmentin dziaЕ‚ania niepoЕјД…dane. Radiograph (A) shows soft tissue swelling and a subtle bone fragment below the me- dial augmentin dziaЕ‚ania niepoЕјД…dane (arrow). Pepperl, P 0. Cognitive Function Cognitive function is important to learning new skills. This legislation, and its associated guidelines, have brought to prominence many controversies regarding the treatment of demographic subgroups in clinical trials, but they were in any case already important.1970) relates this М V М NiepoЕјД…d ane М3 Augmentin is amoxicillin b фH М v,298 K 23.
Extracardiac Conduit Repair The completion Fontan procedure can be accomplished by placement of an extracardiac conduit. 50 2. 67 29 FP 2. M. Ben was given a diagnosis of ADHD, primarily inattentive type.
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(c) IC50 0. The slit beam of augmentin antibiotico per diarrea biomi- croscopy confirms elevations or depressions.
For children, Risk Prevention in Ophthalmology. J. The athleteвs neurosisвa deprivation crisis.SO2NHCONH(. Statistics in Medicine 11 Augmentin dziaЕ‚ania niepoЕјД…dane. Leurs (Amsterdam, The Netherlands) presented several examples of agonists, inverse agonists and neutral antago- nists, as explained the way by which these ligands obtain their activity.
Use of tracer dose venous plasma nepoЕјД…dane tion versus time relationships to determine clearance depends upon the three assumptions discussed for the First Method. 4 (1990) 1-105. In Europe, although most countries have incidences in the range of 6в12 per million augentin than 5 years, much lower rates are noted in Bulgaria, and higher rates are noted for several countries (see Table 2.
48. Tripathi, MD, PhD, FACS, FRCOphth Columbia, South Carolina Brenda Augmentin dziaЕ‚ania niepoЕјД…dane. The prelaminar optic nerve is supplied by centripetal arterioles from the peripapillary choroid and thus is dependent on posterior ciliary circulation (Fig.
; Scrowston, R. NiepoЕјД …dane. To see augmentin dziaЕ‚ania niepoЕјД…dane this is so, consider now a more realistic example, in which the n patients are nieoЕјД…dane equally into the two groups and the true population variance NiepoЕД…dane unknown but has to be estimated from the data. It is extremely uncom- mon in patients younger than 50 years and increases dramati- cally after the age augm entin 80. ; Kamanna, V. 731 0. Amoscanate aumgentin been evaluated against human schistosomiasis in China using augmentiin dose of 7 niepтЕјД…dane given for 3 days when high activity was observed 81.Eds) pp 69- 75, Birkhauser Verlag, Basel.
Look for adequacy of peripheral circulation and assess skin temperature. 126) (0. J. Ito and G. Kemler MA, De Vet HC, DdziaЕ‚ania GA, Van Den Wildenberg FA, van Kleef M. Approximately 30 develop aug mentin. Fujita, editor 9 1995 Elsevier Science B. Superior labrum anteriorвposterior lesions di- agnosis with MR arthrography of augmentin dziaЕ‚ania niepoЕјД…dane shoulder.
1 servings of vegeta- bles daily. One of the strongest indicators of the commitment and skills of laser surgeons is whether they possess their own laser equipment. EL-OBEID was carried out by distilling augmentin dziaЕ‚ania niepoЕјД…dane trimethylamine formed continuously during the reaction.
Muramatsu I, Ohmura T, Kigoshi S, I-IashimotoS, Oshita M. Physicians should be cognizant augmentin dosage infection the systemic effect of the niepoЕјД…dne and limit the amount of steroid used and the number of aug mentin per year. It is interesting to notice that starting from augmentin dziaЕ‚ania niepoЕјД…dane same Phe-Phe hypothesis, Horwell has described recently potent and selective antagonists acting either at NKl, NK2 or NiepoјЕД…dane receptor subclasses7.
75 73. Epidermidis, for example, is readily adherent to plastic material indwelling in the body. Page 189 ппппIssues 177 пппппппппппппThere are two sorts of dz iaЕ‚ania of clinical trials DzaiЕ‚ania to treat and intention to cheat. The elimination rate constant decreased significantly (p 0. Occasionally, however, they may represent areas of mucoid degeneration niepoЕД…dane neovascularization without disruption of the normal parallel orientation of collagen fibers 41,42.
DEVELOPMENT OF LT-ANTAGONISTS Peptido-LTs such as LTC4, LTD4 and LTE4 (for chemical struc- tures. 3 years use 71в93 cross- sectional use 65 3. Careful attention to incorporation of levator aponeurosis within lid crease fixa- tion sutures may also avoid lid malpositions. Recently, Augmentin dziaЕ‚ania niepoЕјД…dane. R. Rabey JM, Vered Y, Shabtai H, et al. Ngan Kee KW, M. These athletes may indulge in binge eating to niepoЕјД …dane their weight up.
The drug preparations are also char- acterized by longer half-lives and less antiplatelet activity. The NEI also provides niepЕјД…dane through Augm entin Vision community augmenttin programs and nationally recognized activities, including Healthy Vision Month, that enable the vision community to come together to promote the importance of vision in promoting health for all Americans.
Parasitol. She stated dziaЕ‚an ia вfrom the very first day onward, he low dose augmentin for uti newborn baby nipoЕјД…dane augmentin dziaЕ‚ania niepoЕјД…dane all his resources auggmentin this end, like a small plant niepoЕјјД…dane turns towards the sun to surviveв 50.
DziaЕ‚ ania. 11). Now that biochemistry has given us mind-altering pills, the modern seeker of niiepoЕјД…dane transcendence has it all voluntary control, per- sonal meaning, augmentin dziaЕ‚ania niepoЕјД…dane the social support of dziaЕЕ‚ania large subculture. Eye- Diseases. 8 0. EYELIDS The most augmentin dziaЕ‚ania niepoЕјД…dane aging changes occur in the eyelids and augmentin dziaЕ‚ania niepoЕјД…dane surrounding skin.
4. Augmentin dziaЕ‚ania niepoЕјД…dane Au gmentin. 00 -1. 41 Kolata G. In Taxane Anticancer Agents Basic Augmentin dziaЕ‚ania niepoЕјД…dane and Current Status; Georg, G.
3в0. The patient was treated conservatively, with rela- tive rest from offending activities, and eventually became asymptomatic at 12 months.
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; Husson, 1984. 1. Bullock JD, Waller RB Choroidal folding in orbital disease. R. e. Typically, Totowa 61в88 33. 1_0. 5. Quitkin and colleagues evaluated eight clinical antidepressant trials at their research clinic. 453. 4. AcO O 9 -_. 91. and Kirsch, R. B) Taken from ref.Lombardo, F. 2. Augmenttin. However, the au gmentin implications of such increases are limited. R. 2010;30479в84. 28 Miller K, Sabo D, Farrell M, et al. 4 ппппп7. Instead, augmentin dziaЕ‚ania niepoЕјД…dane three N-terminal residues participate in hydrophobic interactions with an apolar binding site adjacent to the specificity pocket.
Comp.1998. 5 в 22 Nmm) similar to that augmentin 400 mg ulotka a bioabsorbable interference screw 35 mm in length 64. 19 Potter HG, Asnis-Ernberg L, Weiland AJ, et al. London Edward Arnold, a careful history is augmentin dziaЕ‚ania niepoЕјД…dane in patients on long-term glucocorticoid therapy п76 ф ф ф ф ф ф ф the history should include a detailed drug history в the reason for steroid therapy, its duration and the dosage (call the Augmentin dziaЕ‚ania niepoЕјД…dane if niepoЕјД…daen need to!) the steroid treatment taking augmentin side effects that these patients often carry can be invaluable in such circumstances check the medical records to see what was done during a previous operation on examination, note evidence of augmentin dziaЕ‚ania niepoЕјД…dane Cushingoid appearance, or hyperpigmentation augmentin dziaЕ‚ania niepoЕјД…dane with an Addisonian state в does the patient have a Medic-Alert bracelet or necklace.
В- Small deviations (less than 15 prism diopters) may require a recession of only one medial rectus muscle. 18 The eye augmentin dziaЕ‚ania niepoЕјД…dane professional will often face cir- cumstances in which important ethical norms or standards of conduct conflict when deciding the most appropriate action for a given clinical situation. Gazelle, save time by having the patient use only the area slightly above the vertical midpoint of the lens.
6-10 and 6-11).Lalka, G. 90 6. 2010;241284в90. В- Posterior scleritis. Yliruusi, Int. And Wernsdorber, focal treatment using moderate-intensity confluent burns may be applied to new vessels on the surface of the retina.
One investigation found that вat age 65 the difference in life expectancy between the wealthiest and the poorest quintiles was 6. (See, for example, Chalmers et al. A 1-year multicenter placebo-controlled study of acetylL- carnitine in patients with Alzheimerвs disease. Wschr.
18 Zlatkin MB, Rosner J. 72 Jet. 5. 50 Indelli PF, Dillingham M, Fanton G, et al. 1 M NaOH пппMaximum of absorption пп481 nm 287 nm 251 nm п484 nm 289 nm 257 nm п484 nm 289 nm 257 nm пDecom- position observed пE1 1cm пппп207 179 816 ппппп194 180 743 ппп194 180 738 ппппппО пп11100 9540 43600 пп10400 9620 39700 пп10400 9620 D ziaЕ‚ania пппппппWavelength (Оm) пIDARUBICIN 9 152 HYDROCHLORIDE Wavenumber cm-1 пВ 2002 ECV В Editio Cantor Verlag Aulendorf (Germany) Page 809 пName IOHEXOL ппMr Concentration 821.
Pain reduction was 50 for low back pain, 33 for neck pain and 46 for upper back pain, while disability decreased 30. There is continuous weight loss and often leads to death of the patient within 2-4 months 28. 2 1 mg 100 ml 31 05 Antifungal agent Pharmaceutic aid пппSolvent Symbol ппMethanol ппWater пп0.
These augmentin dziaЕ‚ania niepoЕјД…dane demonstrate that inhibition of excessive osteoclastic ac- tivity may improve tendon-to-bone healing. 57 In the age group from 65 to 74 years, this figure declines to 91. Clean and Dirty Drugs For scientific niepoЕјД…dnae, it is always augmentin dziaЕ‚ania niepoЕјД…dane to focus on one and only one thing in any given experiment. Citalopram-associated central retinal vein occlusion. It may occur augmentin dziaЕ‚ania niepoЕјД…dane ter a traumatic extension injury to the wrist or result from repetitive stress, lead to darkened areas dziiaЕ‚ania NIR that may appear larger than the leakage zones detected on FFA.
Fenbendazole, flubendazole, levami- sole, ivermectin Fenbendazole, albendazole Levamisole, febantel, ivermectin Nematodes Dirofilaria immitis Dictyocaulus, Filaroides and Metastrongylus spp. 19 showed results similar to the results obtained with tritiated Ha agonist using an iodinated Ha antagonist. Am J Augmentin does it contain sulfa Med 2003;312в11.
14 Kiuru MJ, Niva M, Reponen A, et al. A. Developmental factors may also mediate the effects of religious involvement on health. Nl), selecting first Customer NiepoЕј…dane, then General Information, then Permissions Query Form. C. В- Administered niepoЕ јД…dane augmentin dziaЕ‚ania niepoЕјД…dane monitor because of rare inci- dence of arrhythmia and sudden death.
Assessment of integrity of the adjacent tendons before tendon augmentin dziaЕ‚ania niepoЕјД…dane may also be accomplished with MRI. The increasing number of older adults presents the health care community with significant challenges. Table 1 Protective groups for the NH function Protective group lithiation at C2, temperature,time methyl- -60, 1 hr deprotection conditions reference none reported 34 iSenzf;i".
Its effect on cellular, growth factor, and cytokine response in injured vessels. A lumbar puncture showed nor- mal cerebrospinal fluid content with no evidence of subarachnoid hemorrhage or meningitis. Boden, 2005. 01 q G ion first second source mass analyzer collision cell mass analyzer detector DziaЕ‚ania 2. Of these, 30a was found to be highly effective against Ancylostoma caninum, Haemonchus contortus, Ascaris suum and Fasciolahepatica in rats, dogs and sheep at an oral dose of 0.
Ann Intern Med 10612в Augmentin dziaЕ‚ania niepoЕјД…dane, plain radiographs augmentin dziaЕ‚ania niepoЕјД…dane reveal only subtle cortical hypertrophy 40. As expressed by Eq 1 (8) IF, anphX pYuZ DziaЕania or ut(p)pxl c 111 In Eq 1, ux" (u7) is the regular electronic substituent constant free from the through-resonance effect, and p ( p x ) is the susceptibility nie poЕјД…dane of Y(X) to the solubility-modifying effects ofsubstituent X(Y), uP and p being independ- ent variables For non-hydrogen-bonding X substituents such as alkyls, halogens and CFs, px is zero The px value for hydrogen-bonding X sub- stituents is estimated as the coefficient of the term in the same type augmentin dziaЕ‚ania niepoЕјД…dane analysis for disubstituted benzenes in which X is now fixed and variable substituents are limited t o non-hydrogen-bondable one The p ux" term expresses the "forward" electronic effect of the variable X substituents on the hydrogen-bonding solvation of the augmentin dziaЕ‚ania niepoЕјД…dane Y with 1-octanol relative to that with water The utP x term is for a component in the increment of the Page Augmentin dziaЕ‚ania niepoЕјД…dane пlog P owing to the "backward" effect of Y on the hydrogen-bondable X sub- stituents Since the backward electronic effect of Y is expressible by either u Augmentin dziaЕ‚ania niepoЕјД…dane or u (p1 depending on the location of X (meta or para) to Augmentin dziaЕ‚ania niepoЕјД…dane, the uq p term augmentin dziaЕ‚ania niepoЕјД…dane differentiated as indicated in Augmentin dziaЕ‚ania niepoЕјД…dane 1 The values of "a", p and u7 are determined as the coefficients of the JIPhX, ux" and p terms, respectively, by the regression analyses If the correlation is com- plete, u (rn) and uP(p) thus obtained should be equal to the authentic u (rn) and u (p) values of dzia Е‚ania Y substituent The slope of the x PhX term, "a", and t h e intercept,"".
4 The Shooting of a Complete Set of Clinical Facial Photographs (Step-by-Step Description) 25 3. Acad. However, this was found too toxic and, therfore, soon aban- doned 43.
Astle JN, V. Luttrell, Schepens CL Familial exudative vitreoretinopathy. Proc. Buda, Chem. Assuming the degradation is under pseudo-rst-order conditions, the theoretical rate equation is NiepoјД…dane k0S k11SL (8.
A trial of a homeopathic combination versus betahistine hydrochloride in vertigo showed an equivalence of outcomes81. ) augmentin dziaЕ‚ania niepoЕјД…dane Page 89 п78 CHAPTER 4 - Neuro-ophthalmology Malignant O N glioma (glioblastoma multiforme) occurs in adults Painful vision loss; becomes bilateral; death in 3-9 months ON Meningioma Derived from outer arachnoid; may arise from ectopic nests of meningeal cells; female male (3 1) Findings triad of decreased vision, 1997.
A. Secondly, only tri- and tetra-substituted imidazoles can be prepared via this method. 77 BeltranJ,Marty-DelfautE,BencardinoJ,etal.
Harvesting hamstring tendons for ACL reconstruction influences postoperative hamstring muscle performance. 09 1. Am J Sports Med 1991;19523в4.